Similar in appearance to other members of the genus Natalus, this bat resides exclusively in St. Clair Cave, Jamaica, where it feeds on insects.

The genus Natalus was first reported in Jamaica in 1951 by Koopman and Williams, based on a partial mandible collected by H. E. Anthony during his 1919–1920 expedition.

[2] When a live specimen was first encountered in 1959, it was scientifically described by George Gilbert Goodwin as Natalus major jamaicensis.

[3] The type specimen consisted of the skin and skull of a male bat, collected from St. Clair Cave, St. Catherine Parish, Jamaica, by C.B.

[3] The Jamaican greater funnel-eared bat is found exclusively in St. Clair Cave, Jamaica.