In 2015 and 2022 he emerged victorious in the bouts against Anderson Silva and Benjamin Adegbuyi, but were both cut short by Ben Saddik testing positive for banned substances and receiving suspensions, with the fights reversed to a 'no contest'.

[10] He TKO'd Vitaly Oparin in round one at United Glory 15 on March 23, 2012,[10] and followed this up with a fourth-round KO of Nikolaj Falin on June 2, 2012.

In the quarter-finals, he beat Remy Bonjasky on points, but lost via a quick body kick from Daniel Ghiță in the semis.

[12] Despite coming back from the tournament empty-handed, Ben Saddik's stock rose greatly by beating two much higher-rated fighters.

[13][14][15] He started well and floored Aerts in round one, but the Dutchman rallied back and dropped him three times in the second, forcing a referee stoppage.

[28] Ben Saddik rebounded from his DQ loss to Gerges with a first-round knockout win over Mamoudou Keta, during Glory 22.

[30] On August 7, 2015, it was announced that Ben Saddik failed a drug test prior to Glory 23: Las Vegas.

Ben Saddik must also submit clean drugs tests for steroids and diuretics at 30, 10 and 3 days before next fight in Nevada.

[37] On December 8, 2018, he won the Glory 62 Heavyweight Contender tournament[38] by knocking out Benjamin Adegbuyi in the first round of the final, after winning his fights against Junior Tafa and Guto Inocente in the quarter and semi-final respectively.

[45] Ben Saddik was later rescheduled to face Rico Verhoeven at the same event, as a late replacement for Alistair Overeem, who was forced to withdraw due to an injury.

[54] Glory imposed a 6-month suspension on Jamal Ben Saddik for his actions at the semi-final match between Rico Verhoeven and Nabil Khachab during the Glory Heavyweight Grand Prix on 9 March 2024, which ran the risk of inciting violence and could have caused harm to participants, fans and officials.

[55] Ben Saddik was suspended for 10-months for his violations of the anti-doping rules as a result of his positive sample collected out-of-competition on 19 February 2024.

[56] The Anti-Doping Committee determined that a reduction from the default 12-month sanction was appropriate because Ben Saddik provided sufficient evidence that his use of clomifene was pursuant to a valid prescription from a physician to treat symptoms and his use occurred prior to the new ruleset going into effect.

[57] After two and a half years of absence, on February 22, 2025, Ben Saddik is scheduled to face Uku Jürjendal at Glory 98 at RTM Stage in Rotterdam, Netherlands.

His lawyer emphasized though that the arrest of Jamal Ben Saddik has nothing to do with the trade in or possession of prohibited substances such as cocaine[62] (Operation Sky).

[66][67] On June 28, 2024, the Antwerp Criminal Court sentenced Ben Saddik to 40 months in prison and a fine of 40,000 euros for money laundering and fraud.