The James Baxter House is a historic residence in the village of Amberley, Ohio, United States, near Cincinnati.

The Baxter House is a brick structure with some weatherboarding and other wooden elements, set on a stone foundation and covered with a shake roof.

[3]: 82 James Baxter bought the future site of the present house in 1797 as part of a property approximately 0.5 square miles (1.3 km2) in total area.

[3]: 84  The resulting building is approximately 7,000 square feet (650 m2) in area and surrounded by a large lawn with early landscaping and a caretaker's house.

It is one of three Register-listed locations in Amberley, along with the Frank Lloyd Wright-designed Gerald B. and Beverley Tonkens House and the ancient Benham Mound built by the prehistoric Hopewell Indian people.