James DeSana is an American politician.

He is currently serving in the Michigan House of Representatives for the 29th district.

After graduating with a bachelor's degree in business administration from the University of Detroit Mercy in 1987, DeSana worked in the fastener manufacturing industry for over 36 years.

[3] He is the son of James DeSana Sr., Downriver's senate representative from 1976 to 1986.

[4] DeSana ran to represent the 29th district of the Michigan House of Representatives in the 2022 Michigan House of Representatives election, winning with 18,042 votes and 51.5% of the vote.