[6][7] Little cites Joan Mitchell along with Barnett Newman, Mark Rothko, Franz Kline, Alma Thomas, and George L. K. Morris as among the artists whose work he most admires.
[11] In 1976, his work was the subject of the solo exhibition Paintings by James Little curated by Ronald Kutcha at the Everson Museum in Syracuse.
Riders at Jamaica Station now travel through his 85-foot-long environment made of 33 multicolored laminated glass panels in a prismatic design, each measuring at 17-feet tall by 5-feet wide.
[4][15] In 2020, some of Little's large-scale black-tone paintings were shown in a two-artist exhibition with the work of Louise Nevelson, who was represented exclusively by the black colored sculptures, for which she is most known.
The exhibition titled Louise Nevelson + James Little ran from September 3, 2020 until October 28, 2020 at Rosenbaum Contemporary in Boca Raton, Florida.
[22] In 2019, Little curated the New York Centric exhibition at the American Fine Arts Society gallery, which included the work of multiple generations of abstract artists associated with New York City, among them Alma Thomas, Alvin Loving, Larry Poons, Stanley Boxer, Peter Reginato, Dan Christensen, Ronnie Landfield, Gabriele Evertz, Charles Hinman, Thornton Willis, Doug Ohlson, Robert Swain, and Ed Clark.