James Malone House is a historic home located near Leasburg, Caswell County, North Carolina.

It was built in 1861, and is a two-story, three bays wide, Italianate style frame house on a brick foundation.

It has a hipped roof and features a two-story pedimented entrance porch and brick end chimneys.

The interior and exterior features woodwork attributed to noted African-American cabinetmaker Thomas Day.

This article about a property in Caswell County, North Carolina on the National Register of Historic Places is a stub.