[5][6][7] Poyser has written and produced songs for numerous artists including Erykah Badu, Mariah Carey, John Legend, Rihanna, Lauryn Hill, Common, Anthony Hamilton, D'Angelo, the Roots, Jill Scott, Al Green, Emeli Sandé, Talib Kweli, Big Sean, and Andra Day, among others.

Throughout his career, Poyser has toured and played for with high-profile artists including DJ Jazzy Jeff & The Fresh Prince, Cece Peniston, Jay-Z, Usher, Queen Latifah, D'Angelo, Elvis Costello, Hezekiah Walker, and Aretha Franklin, among others.

An active session musician, he has contributed to the works of prominent musical acts such as Adele, Norah Jones, Eric Clapton, Elton John, Ozzy Osbourne, Nas, Ziggy Marley, Citizen Cope, Yebba, Snoh Aalegra, and Femi Kuti among others.

In film, he composed the score for the Academy Award-winning Two Distant Strangers, Boxing Day, and Totally Awesome, while contributing music and arrangements of Fame, Dave Chappelle's Block Party, and Jeymes Samuel's The Harder They Fall and The Book of Clarence (both for Netflix).

He also scored the Hulu docu-series, The 1619 Project and the WNBA documentary, Unfinished Business by Alison Klayman, in addition to serving as a composer for the CBS television series, The Equalizer.