The James W. Hamer House is a historic home located near Little Rock, Dillon County, South Carolina.

It was built in 1910–1911, and is a large two-story, three-bay, brick-veneered Neo-Classical Revival style residence.

The front facade features an Ionic order pedimented portico supported by two sets of paired brick columns.

Also located on the property are several agricultural outbuildings and a mature pecan orchard that was likely planted by about 1920.

This article about a property in Dillon County, South Carolina on the National Register of Historic Places is a stub.