James Wedderburn (1495?–1553), a poet and playwright and early Scottish proponent of Protestantism, was his grandfather.
[1] In February 1626 he was appointed rector of Compton, diocese of Winchester, and was collated canon of Ely before Christmas 1626.
Made D. D. by the University of Cambridge in 1627,[2] he was presented by the king to the vicarage of Mildenhall, diocese of Norwich, on 12 September 1628.
[4] When the Glasgow assembly of 13 December 1638 deposed the bishops, Wedderburn was expressly included in the excommunication, because "he had been a confidential agent of Laud, archbishop of Canterbury, in introducing the new liturgy and popish ceremonies".
He fled to England, in company with other Scottish bishops, and found protection from his patron, Archbishop Laud; but he did not long survive his deprivation.