Jamestown Downtown Historic District is a national historic district located at Jamestown in Chautauqua County, New York.

Located in the district is the separately listed Wellman Building.

Other notable buildings include the Arcade Building (1898), Odd Fellows Lodge (1914), Bank of Jamestown (1918, 1924), Hotel Samuels (1910), Hotel Jamestown (1924), Chautauqua School of Nursing (1911), Jamestown Telephone Company (1930), Maddox Building (1933), First National Bank (1953), Pennsylvania Gas Company building (ca.

1955), Chautauqua National Bank (1956), Palace Theatre (now the Reg Lenna Center for the Arts, 1923), Allen's Opera House (now Lucille Ball Little Theatre, 1875), and the former Broadhead Worsted Mills (ca.

This article about a historic property or district in Chautauqua County, New York, that is listed on the National Register of Historic Places, is a stub.