Jamieson and Spearl was a St. Louis, Missouri architectural firm that designed most of the buildings built at Washington University in St. Louis and the University of Missouri in Columbia between 1912 and 1950.
He then joined his brother Thomas Paterson Jamieson in an architectural practice R.G.
He received the first University of Pennsylvania Traveling Scholarship to study in Europe at the Victoria and Albert Museum.
After Cope's death in 1902 he returned to Philadelphia but continued to maintain a practice in St. Louis.
In 1912 he formed his own practice was joined in 1918 by George Spearl (died 1948), another Scottish-born Cope alumni.