In 1915, Jane appeared with Valeska Suratt in The Soul of Broadway at Fox Studios.

They both appeared in A Daughter of the Gods (1916), with Katherine's dramatic performance earning praise as a "child prodigy" and a "three-foot Fiske.

"[7] In 1917, Jane and Katherine starred in two of Fox's "kiddie films", Troublemakers and Two Little Imps.

[8] In 1919, the Lee sisters made the list in the Top Ten Money Making Stars Poll.

Jane later had uncredited roles in the sound motion pictures Knock on Any Door (1949), Cheaper By the Dozen (1950), and Comin' Round The Mountain (1951).