In the show, after graduating from Sacred Heart High School, Janice joined an ashram in Venice, Los Angeles, the character adopting the name Parvati Wasatch.

She worked as a furniture mover and at an espresso bar in Olympia, Washington before finally moving back to New Jersey permanently.

Janice is portrayed as a chronic malingerer, with the people around her often holding the opinion she is lazy and has no work ethic, filing for disability benefits in Washington for alleged carpal tunnel syndrome, and using her claim of newly contracted Epstein–Barr to excuse herself from her household duties.

Her relationship with Tony is often shown to be strained in nature, as he still holds her responsible for abandoning the family and leaving him to deal with their abusive mother alone.

Her high school boyfriend, Richie Aprile (David Proval), is a DiMeo crime family capo who is released from prison around the same time.

Tony visits her at the hospital and angrily tells her that since she has been assaulted, he is now forced to retaliate and risk facing a war with the Russians or else lose respect.

Janice's next phase is marked by a brief interest in a Christian music career, as well as an equally brief live-in relationship with her narcoleptic boyfriend, Aaron Arkaway (Turk Pipkin).

After Ralph happily tells her that he is no longer seeing Rosalie Aprile and plans to move in with her, Janice responds by flying into a rage, pushing him down a flight of stairs and screaming at him to leave.

Following Ralph's disappearance, Janice sets her sights on the newly widowed Bobby Baccalieri (Steve Schirripa), another of Tony's caporegimes, whose fidelity to his wife while she was alive, and obvious adoration of her after her death makes him especially appealing.

While it briefly has the desired effect, Tony, in doubt and jealous of Janice's newfound peace of mind, purposefully obstructs her progress by taunting her about her missing son.

In the show, Tony angrily confides to Dr. Melfi (Lorraine Bracco) that Janice "gets nothing" because she didn't hold the same trauma and scars from their mother since she left home almost immediately after high school.

Later in the episode, Tony lets go of his hostility and compensates Janice and Bobby by persuading an imprisoned John Sacrimoni (Vincent Curatola) to sell them his house at half price.

Soon after that conversation, Bobby is murdered by the hitmen of Phil Leotardo (Frank Vincent) while buying a model train in a hobby store, making Janice a widow.

This prompts Tony to make a deal with "Uncle Pat" ensuring Junior's estate will go into a trust that will benefit Bobby's children and not Janice.