In 1963 he completed the post-graduate courses for Opera and Symphony Orchestra Conducting under Professor Odysseas Dimitriadis at the same institution.

From 1982 until 2002 Djansug Kakhidze was the Artistic Director and Chief Conductor of the Tbilisi Opera and Ballet Theatre.

Opera performances released under his direction included Salome, Don Giovanni, Boris Goduno, Il trovatore, Otello, Rigoletto, Cavalleria rusticana, Gianni Schicchi, L'elisir d'amore, The Queen of Spades, The Fiery Angel, The Love for Three Oranges, Duenj, Abesalom and Eteri, and Music for the living.

He established the first professional boys' choir in Tbilisi at this center in 2000, further developing the classical performing arts in Georgia.

His performance of Berlioz's Damnation of Faust with the Orchestre de Paris in 1990 drew high praise from critics, and helped him to secure further international success in places such as the United States, where appeared as a guest conductor with both the Boston Symphony Orchestra and the National Symphony Orchestra.