National Route 6 (国道6号, Kokudō Roku-gō) is a Japanese highway from Tokyo to Sendai that goes through the cities Mito, Iwaki and Sōma.

It traces the old Mito Kaidō route from Tokyo to Mito,[2][3] and, for much of its 353.6-kilometer (219.7 mi) route, it runs parallel to the Jōban railway line and the Jōban Expressway.

Originating in Chūō, Tokyo (at Nihonbashi, which also marks the origins of Routes 1, 4, 14, 15, 17 and 20), it ends in Miyagino-ku, Sendai (at the Nigatake interchange, junction with Route 45, also the origin of Route 47) Major cities and villages it passes through include: Kashiwa, Toride, Tsuchiura, Ishioka, Mito, Hitachi, Iwaki, Tomioka, Ōkuma, Sōma, Watari, Iwanuma The actual terminus is Iwanuma in Miyagi (at the Fujinami intersection) which is the junction of Routes 4 and 6.

[4] National Route 6 is a part of the lengthened Tōkaidō[clarification needed] which connects the Kansai region (Kinai), or Nara and Kyoto in particular, and the Pacific coast of Tōhoku (called the Tagajō).

On 12 March 2011, access to a large section of National Route 6 was restricted due to the Fukushima Daiichi nuclear disaster between Hirono and Haranomachi.