Mayasan Maru made a second voyage with convoy B-2 carrying IJA troops from Pusan to Rabaul in February.

She avoided damage in the 12 July 1944 attack by USS Apogon and Piranha while transporting these troops to the Philippines with convoy MOMA-01.

She similarly avoided damage when return convoy Hi-68 was attacked by USS Crevalle, Flasher and Angler on July 25 and 26.

The convoy sailed into the South China Sea from Mako naval base in the Pescadores on 17 August,[2] and was discovered that evening by USS Redfish.

Redfish assembled USS Rasher, Bluefish and Spadefish for a radar-assisted wolfpack attack in typhoon conditions on the night of 18/19 August.

[2] At 18:15 on 17 November 1944 at position 33°17′N 124°41′E / 33.283°N 124.683°E / 33.283; 124.683, the Mayasan Maru was torpedoed by the USS Picuda in rising seas, and sank in two and a half minutes taking with her 3,536 men.