In between his work with Spiritualized and Spacemen 3, Pierce has been active with a network of free jazz players and improvisers, collaborating with artists, including Black Rebel Motorcycle Club, Dr. John, Primal Scream, Daniel Johnston and Yoko Ono.

Also in 2006, he composed the original score for an art installation called "Silent Sound"[2] by British artists Iain Forsyth and Jane Pollard.

The live performance at St. George's Hall in Liverpool was recorded and released as a limited edition signed and numbered CD.

Between 6 and 8 February 2007, Pierce performed in a series of benefit concerts for the HOPING Foundation for Palestinian children.

[7] Both his lungs had filled with liquid; the 5′ 11″ (180 cm) musician's weight plunged to seven stone (44.5 kg; 98 lbs), and his heart stopped beating twice.