In 1865, remnants of a Roman settlement were uncovered in Repišće, Klinča Sela, a village in Jastrebarsko metropolitan area.

Further archeological investigation in the late 20th century classified them as a villa rustica and a necropolis consisting of six tumuli, both dating to the early Roman Empire period.

The location of this archeological site on the fluvial terraces of the local Konjava stream[i] is attributed to the peaceful state of the central Roman Empire, which in turn led to formation of settlements in river valleys.

'Saint Mary under Okić') (locally nicknamed Grič), an archeological site located some 2.5 kilometers (1.6 mi) north of Repišće dating to 4th century, shows a migration from easily accessible locations to steeper hills and creation of isolated walled refugia.

A remnant of falconry can also be found in the Jastrebarsko coat of arms, which features a yellow goshawk on a blue blackground.

In 1257 Croato-Hungarian King Bela IV awarded Jastrebarsko the status of a "free royal trading center" (Croatian: slobodno kraljevsko trgovište) by the means of a golden bull.

The local elementary school, founded in the 17th century, was augmented by a number of other cultural, social and sports organization, including a library, the singing society "Javor", association of tamburica players, a volunteer fire brigade and a theater and others.

The town was the site of a concentration camp for Serb children operated by the authorities of the Independent State of Croatia during World War II, from mid-July to August 1942.

Preliminary opinion by Dadić called for construction of four additional interchanges on the Zagreb–Karlovac stretch that would stop Jastrebarsko from being the bottleneck exit for all commuters living on the A1 corridor.

There are scientifically documented claims that the global warming affects the climate in Jastrebarsko by increasing average yearly temperature by 1.2 °C (2.1 °F).

The area is fairly large at 628 square kilometers (242 sq mi), but has a low population density and encompasses only 29,697 people.

Jastrebarsko was home to two important Croatian Roman Catholic cardinals: Aloysius Stepinac (1898–1960) and Franjo Kuharić (1919–2002).

Born in a nearby village, Kupinec, Maček led the Croatian Peasant Party fighting for the independence of Croatia since the assassination of Stjepan Radić until World War II and the establishment of the Independent State of Croatia by the Axis powers which defeated the Kingdom of Yugoslavia in 1941.