Guerra began his career as an infielder, reaching MLB as such in 2018 with the San Diego Padres, before converting to pitching in 2019.

He has also played in Major League Baseball (MLB) for the Tampa Bay Rays and Milwaukee Brewers.

[1] At the time Guerra drew mixed reviews for his defense because he had fringy speed, but he showed a very quick first step and excellent range to both sides.

He had very soft but quick hands and was assured in the field, which complemented his arm, perhaps the strongest in the Red Sox system.

[2] On November 13, 2015, the Red Sox traded Guerra, Carlos Asuaje, Manuel Margot, and Logan Allen to the San Diego Padres for Craig Kimbrel.

[5] Guerra spent 2016 with the High-A Lake Elsinore Storm, where he batted .202/.264/.325 with nine home runs and 41 RBIs in 105 games, as on defense he made 30 errors at shortstop and had a .940 fielding percentage.

[6] He spent 2017 with Lake Elsinore and the Double-A San Antonio Missions, batting .222/.266/.349 with nine home runs and 53 RBIs in 128 games between both teams.

He had allowed four runs in 2 innings pitched two days prior against the Arizona Diamondbacks, his only appearance for the Padres in 2022.

[25] In 6 appearances for the Rays, Guerra surrendered 2 runs across 5 innings pitched (3.60 ERA), walking 9 and striking out 4.

[32] He pitched for Panama in the 2023 World Baseball Classic, earning a save and not allowing a run in 2 appearances.