Alford was also a member of the Oakland Raiders, Seattle Seahawks, Virginia Destroyers, and Saskatchewan Roughriders.

In 2007, Alford served as the Giants' long snapper during field goal attempts, due to a season-ending injury to Ryan Kuehl.

[1] Alford won Super Bowl XLII in his first season, sacking Tom Brady in the final minute of the Giants' 17–14 win over the New England Patriots.

He was a three-year starter who was selected First-team All-State, U.S. Army All-American and was listed among the G&W Recruiting Report Top 50 defensive players in the nation.

He was selected for Penn State's Jim O’Hora Award which honors the defense's most improved player each season.

Alford's most memorable moment with the Giants was a devastating sack of Tom Brady in Super Bowl XLII.

With less than one minute remaining in the game and the New England Patriots down 17–14 with possession of the ball, Alford sacked Brady resulting in a 3rd and 20 situation.

The Giants went on to shock the previously undefeated Patriots 17–14 in what's widely considered one of the greatest upsets in Super Bowl history.