Formerly, he served as the director of the Johns Hopkins Center for Neurogastroenterology and was the founder and co-director of the Amos Food, Body and Mind Center, Vice Chair of Medicine for Innovation and Commercialization in the Johns Hopkins School of Medicine, and Professor of Innovation Management at the Carey Business School.

He trained in internal medicine and pulmonology at Georgetown University-DC General Hospital and Tufts University-New England Medical Center.

[1] After completing his fellowship in gastroenterology, Pasricha was appointed chair of the University of Texas Medical Branch in 1997, where he held the Bassel and Frances Blanton Distinguished Professorship in Internal Medicine.

His clinical and research interests include GI motility disorders and abdominal pain, and the development of novel endoscopic procedures and devices[2] Amongst his notable contributions to gastroenterology are the introduction of botulinum toxin as a therapeutic agent for gastrointestinal disorders, including achalasia[3] and sphincter of Oddi dysfunction.

[7] Notably, he demonstrated that the enteric nervous system is in a state of continual turnover, identifying the stem cell responsible for that in mice studies.

He served on the National Commission on Digestive Diseases, appointed by the United States Congress to provide a roadmap for progress in gastrointestinal disorders.