[3] The district share boundaries with Karimnagar, Mancherial, Peddapalli, Hanamkonda, Warangal, and Mulugu districts and with the state boundary of Maharashtra and Chhattisgarh.

The world's largest multi-stage lift irrigation project Kaleshwaram Lift Irrigation Project is in Jayashankar Bhupalpally District and Jayashankar Bhupalpally District falls Under naxal affected district as per Red corridor.

The district is spread over an area of 6,175 square kilometres (2,384 sq mi).

[8] The district will have One revenue division of Bhupalpally and is sub-divided into 11 mandals.

[3] Bhavesh Mishra, IAS is the present collector of the district.