However she had already gained a foothold in the industry, as a child artiste in Sangeet Samrat Tansen, Zameen Ke Taare (1960) and Pyar Ki Pyaas (1961).

[1] She adopted the name of "Jayshree T" based on her original surname of Talpade though her last name was in time Karnataki as she later married.

Initially, she wanted to become a doctor, but film director Amit Bose cast her in a dance sequence for Abhilasha in 1968, after she was recommended by choreographer Harmendar.

Jayshree has acted in various Indian languages including Bengali, Tamil, Telugu, Malayalam, Kannada, Marwadi, Rajastani, English, Sindhi, Assamese, Bhojpuri, Oriya, Haryani, Garyali, Nepali, Punjabi, Marathi and Gujarati.

She has performed on stage with Mohammad Rafi, Manna Dey, Mukesh and Asha Bhosle.

Citing an incident which took place in a remote place of Gwalior, while shooting for a song, in an interview in 2012, Jayshree is quoted to have said: "We were shooting at a remote spot in Gwalior, for Kasam Bhavani Ki (1981), in which Yogeeta Bali played the female lead.