Jayne founded and launched the Ozanne Foundation in 2017 which works with religious organisations around the world on prejudice and discrimination of LGBTQI people.

[5] After completing her postgraduate program and being a visiting research fellow at the Department of International Development, University of Oxford (2007–08) she moved in to fundraising.

"[4] She resigned as a member of the government's LGBT+ advisory panel in March 2021, accusing equalities ministers Liz Truss and Kemi Badenoch of "creating a 'hostile environment' for lesbian, gay, bisexual and transgender people" and "claiming she had sat in meetings with the pair and 'been astonished about how ignorant they are'".

[10] In November 2021 at Middle Temple, Ozanne participated in a debate on conversion therapy with CEO of Stonewall Nancy Kelley and "gender-critical" barrister Naomi Cunningham.

[13] Members of the board include Dr Jagbi Jhutti-Johal, Anil Bhanot, Ursula Halligan, Dilwar Hussain, Laura Janner-Klausner, Frederick Hyde-Chambers, Hannah Brock Womack, Revd David Mayne, and Revd Michaela Youngson.

[13] In December 2021, the Ozanne Foundation Awards presented awards to Gregory Cameron, Alicia Kearns, Helena Kennedy, Baroness Kennedy of The Shaws, and Jeremy Marks, for what Bayes described as "significant impact on the lives of LGBT+ people, particularly those living in faith settings".

[12] Having previously believed that being Christian and being gay were not compatible, Ozanne sought a deliverance ministry and underwent an exorcism.

[4] In 2009, after years of personal struggle as an evangelical Christian trying to reconcile her faith with her sexuality, Ozanne came out as gay to her friends and family.