[citation needed] Following his freshman year Jayson attended the Pittsburgh Penguins development camp and on August 1, 2012 he signed a two-way contract with an annual value of $925,000.

[4] On July 1, 2015, Megna left the Penguins organization as a free agent and signed a one-year, two-way contract with the New York Rangers.

[8] With his contract with the Rangers completed, Megna secured a one-year, one-way deal as a free agent with the Vancouver Canucks on July 1, 2016.

As a free agent from the Capitals, Megna agreed to one-year, two-way $700,000 contract with his fifth NHL club, the Colorado Avalanche on July 1, 2019.

[14] After attending his first Avalanche training camp, Megna was amongst the last cuts re-assigned to begin the 2019–20 season with AHL affiliate, the Colorado Eagles.

Collecting 4 points through his first 8 games, Megna was recalled to the NHL and made his Avalanche debut in a 4-3 overtime defeat against the Florida Panthers on October 30, 2019.

[18] Megna remained on the Ducks roster for the duration of the season and made his most NHL appearances since 2017, in finishing with 2 goals and 8 points in a combined 55 games.

[19] Towards the end of a successful year with the Providence Bruins having recorded 19 goals and 37 assists through 69 appearances, Megna was rewarded for his efforts with a recall to the NHL club on April 16, 2024.