Apart from the ruined fortifications, there is little sign now that in the 15th and 16th centuries this was a thriving trading centre, on major international mercantile routes between the Black Sea and Northern Europe, and host to multiple merchant families of diverse ethnicities and religions.

In 1406 king Władysław II Jagiełło presented Jazłowiec to starosta Dziersław Konopka, who under pressure from the Grand Duchy of Lithuania, in the person of Witold Kiejstutowicz, ceded the domain to Teodoric Buczacki Jazłowiecki.

In 1615 the Jazlowiecki family issued privileges encouraging Armenian refugees from Crimea to settle in the town, as happened in Kamieniec Podolski (now Kamianets-Podilskyi), since the community brought in increased trade and hence income to the locality.

[6] 1644-1659 saw the extension of the fortress by Hetman Stanisław Koniecpolski and his son, Aleksander, to whom the Sejm of 1658 granted the right of collecting customs charges for maintaining an armed garrison.

In 1746 the town was acquired by Stanisław Poniatowski who built the extant palace on the lower ramparts of the fortress and probably used them as building material for his elegant project.

[11][12] In 1772, the town was politically "detached" from Poland, and occupied under Austrian rule, the policies of Emperor Joseph II led to the closure of both monasteries.

[2] The nearby fortified town of Buczacz, 13 kilometres to the north of Jazłowiec, was an important centre of Jewish life and scholarship for four centuries or more, since 1572.

[13] In 1863, Krzysztof Błażowski donated his palace and estate to the Polish noblewoman, widow and mystic, Marcelina Darowska, for the establishment there of a convent for her religious order, the Congregation of the Sisters of the Immaculate Conception of the Blessed Virgin Mary, and a girls secondary school and other educational provision for the local population.

[2] The Sisters swiftly established the boarding school in Jazłowiec itself, for the children of wealthy families and which was attended by Darowska's own daughter, Karolina.

In 1893 the priest appointed to the Catholic parish of St. Anne in Jazłowiec and to be chaplain to the order and the school was Adam Sapieha (1867-1951), future cardinal and Archbishop of Kraków (1911-1951) and Senator of the Sejm.

Between 11–13 July 1919 a three-day-long battle was fought for the town by Poles and Ukrainians locked in a fratricidal conflict, each trying to secure their statehood.

In 1945, the town was downgraded to the status of a village and renamed Yablunivka, (or Yablonovka in Russian), and most of its Polish residents were forcibly deported for resettlement in the so-called Recovered Territories in Western Poland.

Following the collapse of the Soviet Union and the emergence of independent Ukraine after half a century, its earlier Ukrainian name was restored and the convent was revived.