Jean-Baptiste Salpointe (French pronunciation: [ʒɑ̃ batist salpwɛ̃t]; February 22, 1825 – July 15, 1898) was the first Bishop of Arizona and the second Archbishop of Santa Fe.

Among his accomplishments at Mora was his success in persuading the Sisters of Loretto and the De La Salle Christian Brothers to come to the parish and establish schools there.

At the time Arizona consisted of approximately 6,000 settlers in some half a dozen settlements and several mining camps, as well as the Native Americans that inhabited the territory.

Salpointe set about building churches, organizing new congregations, and founding schools and hospitals in the territory.

Archbishop Salpointe retired on January 7, 1894, and moved to Tucson, where he wrote a history of the Catholic Church in the Southwestern United States.