He was Minister of Justice and Religious Affairs (1834–1837) during the July Monarchy, a peer of France (1839) and Councillor of State (1852).

[citation needed] Under the Bourbon Restoration (1815-1830) Persil participated in the struggles of the Liberal party.

He protested against the ordinances of Charles X of France, and supported making the Duke of Orleans Lieutenant-General of the kingdom.

As deputy and magistrate Persil supported the conservatives and fought the democratic liberal party with great energy.

He attacked the republican clubs and newspapers, denounced conspiracies and meted out severe punishments.

[1] On 4 April 1834 Persil was called by Louis Philippe to replace Félix Barthe as Minister of Justice and Religious Affairs.

He ran again for election due to this appointment, and was returned on 15 May 1834 and then on 21 June 1834 in three districts, choosing to represent Condom.