Though Frank never received any formal training or education in the design field, his use of natural materials and simplicity were widely favored.

[3] Frank sought to design spaces that were uncluttered, featured neutral color schemes, and exotic patterns.

His idea of simplicity extended to everything including his wardrobe; having owned forty of the exact same gray flannel shirts.

"[5] Throughout his career, Frank collaborated with designers and artists, such as, Diego Giacometti, Salvador Dalí, Emilio Terry, and Christian Berard.

In 1924, Frank was commissioned by Jean Rene Guerrand to design a unique collection of home furniture.

Frank challenged his students to create a table that would retain its integrity whether sheathed in gold leaf, mica, parchment, or even painted burlap.

His search for lines, curves, and mixing of materials lead him to the Nelson Rockefeller's lavish Fifth Avenue apartment in New York in 1937.

The Rockefeller living room included expensive furnishings, Aubusson rugs, armchairs, and thirteen meters of green and white hand woven silk delivered from France.

"Reports from refugees about the persecution of homosexuals and Jews prompted Jean-Michel Frank to leave Paris in 1940.

By way of Lisbon, he emigrated to Buenos Aires..."[7] In Argentina, Jean-Michel Frank worked with his old friend and business associate, Ignacio Pirovano, on several private and commercial projects.

[8] Jean-Michel Frank kept his private apartment in Buenos Aires on the top floor of the company of which he was the Artistic Director[9] in Argentina.

Frank's lights were classic-modern combined with exotic, textured materials, such as, plaster, mica, obsidian, vellum, and terracotta.

[11] Throughout his life, Frank was troubled by loss, depression, drug addiction, homophobic taunts and anti-Semitism.