Jean-René Lisnard (born 25 September 1979) is a French-Monegasque retired professional tennis player who formerly represented France.

He is to date, the only Monegasque tennis player to have won a match in the main draw of a Grand Slam tournament.

In May at the 2009 French Open, he lost his first-round match to Israeli player Dudi Sela 6–4, 6–3, 4–6, 6–3.

Lisnard qualified for the main draw of the 2011 US Open and defeated Olivier Rochus of Belgium in straight sets to advance to the second round.

He lost to Germany's Florian Mayer in straight sets in the second round.