She was the daughter of Charles Angibaud, formerly Louis XIV's apothecary and also a Huguenot who had left France in 1681, shortly before the revocation of the Edict of Nantes in 1685.
The same year, he passed the three-part examination (physiology, pathology and therapeutics) to become a licentiate of the Royal College of Physicians.
Biographer Miriam Austin Locke has noted that "although a qualified practitioner, he was ridiculed as a quack because of the peculiarity of his foreign manner and his strange methods of practice.
Strikingly tall and thin, he was ridiculed for his fondness for alcohol, his outlandish manners, and his thick French accent: Watteau quoted his saying "Prenez les pilules".
He was the model for the doctor in William Hogarth's The Harlot's Progress (Plate 5), and he is one of four physicians held up for ridicule in Henry Fielding's Tom Jones.