[3] Born in Craiova, Negulesco was the son of a hotel keeper and attended Carol I High School.

[6] He became interested in movies and made an experimental feature film, financed as well as written and directed by himself, called Three and a Day.

[7] He did the opening montage for the film musical Tonight We Sing and worked on The Story of Temple Drake and A Farewell to Arms (1932).

During his Hollywood career and in his 1984 autobiography Things I Did and Things I Think I Did, Negulesco claimed to have been born on 29 February 1900; he apparently was motivated to make this statement because birthdays on leap year day are comparatively rare (and even though 1900 was not a leap year in the Gregorian calendar, it was under the Julian calendar, which applied in Romania at that time).

From the late 1960s, Negulesco lived in Marbella, Spain, where he died, at age 93, of heart failure.