She was a daughter of John II, Count of Vendôme[1] and Isabelle de Beauvau.

[clarification needed] Her paternal grandparents were Louis, Count of Vendôme and Jeanne of Laval.

She married first John II, Duke of Bourbon in 1487.

On 11 January 1495, Jeanne married her second husband John III, Count of Auvergne.

On March 27, 1503 she married her third and final husband, François de La Pause, baron de la Garde.