George Leo "Jeff" Jefferson (August 8, 1922 – September 21, 1985) was an American baseball pitcher in the Negro leagues.

He played with the Jacksonville Red Caps in 1942 and 1943 and the Cleveland Buckeyes from 1944 to 1950.

His brother, Bill Jefferson, also played Negro league baseball.

This biographical article relating to an American baseball pitcher born in the 1920s is a stub.

You can help Wikipedia by expanding it.This Negro league baseball pitcher article is a stub.