[1] Promoted to the first team for the 2016 season, he made his senior debut on 10 April of that year, starting in a 5–3 Campeonato Goiano away win against Trindade.
[2] Jefferson made his Série B debut on 13 May 2016, playing the full 90 minutes in a 1– away defeat of Tupi.
[3] Regularly used in his first year, he subsequently became a backup option, contributing with only two league matches in Goiás' promotion campaign.
Jefferson became a first-choice for the 2019 season, and made his Série A debut on 28 April, starting in a 1–0 away win against Fluminense.
[4] He scored his first goal in the category on 10 June, netting his team's second in a 3–1 home defeat of Chapecoense.