[3] The Main Campus is located in Jefferson County, with a portion in the city of Hillsboro and most of it in an unincorporated area.

JC Online, was formally established in 2010 as the college's virtual campus, providing a full range of classes and e-services to students who prefer this highly popular method of instruction.

The 40,000 square feet (3,700 m2) facility is located at 1687 Missouri State Road behind the Arnold Library and Recreation Center.

The 20,000 square feet (1,900 m2) building is located at 4400 Jeffco Boulevard and is home to the Law Enforcement Academy, EMT-Paramedic programs.

[7] Founded in 1991, the Foundation supports the educational opportunities at Jefferson College by hosting events.

Jefferson College Television (JCTV) provides educational opportunities in broadcast journalism.

The library's collection includes print periodicals, best sellers, graphic novels, DVDs, music CDs, eBooks and audiobooks.