Located within the West Adams district,[1] there are fourteen Los Angeles Historic-Cultural Monuments in the neighborhood, and in 1987, the 1923 Spanish Colonial Revival Jefferson Branch Library was added to the National Register of Historic Places.

[4] Centered along Jefferson Boulevard, the neighborhood is home to Craftsman bungalows, brick warehouses, colorful wall murals and small storefronts.

[5] After the 1948 Supreme Court ruling that banned racial covenants on property - Shelley v. Kraemer - many of Jefferson Park's white residents left the neighborhood, in turn being replaced by upper-middle and upper-class African-Americans.

[6][7] The resulting area was dubbed "Little New Orleans" and contained a number of Creole-owned businesses such as the Big Loaf Bakery and Harold and Belle’s, an upscale Creole restaurant.

The Conservancy stated: "The farmhouse is now the oldest remaining house in the West Adams neighborhood of Jefferson Park, and the last link to the area’s agricultural history.

The Jefferson Park Historic Preservation Overlay Zone (HPOZ) was adopted by the Los Angeles City Council in 2011.

Mexico and El Salvador were the most common places of birth for the 32.7% of the residents who were born abroad, considered an average percentage of foreign-born when compared with the city or county as a whole.

[16] Jefferson Park residents aged 25 and older holding a four-year degree amounted to 11.8% of the population in 2000, considered low when compared with the city and the county as a whole; the percentage of residents aged 25 and older with a high school diploma was also considered low.