The Jefferson Trust Company is a historic building located in Hoboken, Hudson County, New Jersey, United States.

The building was built in 1912 and was added to the National Register of Historic Places on February 13, 1986.

[3] The original trust company failed during the Great Depression and the building passed on to a succession of owners.

Much of the original plaster interior remains intact.

This article about a property in New Jersey on the National Register of Historic Places is a stub.