Jeffrey Siewerdsen did his undergraduate studies at the University of Minnesota in Minneapolis, MN, where he received his Bachelor of Arts degree in Physics and Astrophysics with a minor in Japanese in 1992.
Siewerdsen's doctoral research involved early development of amorphous silicon Flat panel detector for medical x-ray imaging under the supervision of Professor Larry E. Antonuk.
Siewerdsen's work focused on the development of early flat-panel detector systems for diagnostic radiography, fluoroscopy, and mammography as well as megavoltage portal imaging for guidance of radiation therapy.
His doctoral dissertation[8] established mathematical models for the signal-to-noise properties (specifically, the modulation transfer function, noise-power spectrum, and detective quantum efficiency) of flat-panel x-ray detectors.
He also collaborated closely with Dr. Kristy Brock on deformable image registration using the Demons algorithm[17][18] and with Dr. Narinder Paul on development of dual-energy chest radiography systems for detection of early stage lung cancer.