After a world premiere run in Houston, Texas, the musical embarked on a national tour of the United States prior to its Broadway debut in 1997.

However, a concept recording was made featuring Colm Wilkinson as Dr. Henry Jekyll/Edward Hyde and Linda Eder as Lucy Harris and Lisa Carew.

The show was subsequently re-written by Wildhorn and Leslie Bricusse and a world premiere production was announced for 1990 in Houston, Texas.

[1] Jekyll & Hyde was first presented at the Alley Theatre in Houston, Texas, in May 1990 where it broke box office records, played to sold-out houses, and won acclaim from critics leading to the run being extended twice, finally closing in July 1990.

Chuck Wagner played the title roles, with Rebecca Spencer as Emma Carew (then named Lisa) and Linda Eder as Lucy.

[3] Due to the success of both runs, the musical embarked on a national tour of the United States from August 1, 1995 (beginning in Dallas, Texas) through April 1, 1996 (ending in Baltimore, Maryland)[4] The cast included Robert Cuccioli (Dr. Jekyll/Mr.

Hyde), Linda Eder (Lucy Harris), Christiane Noll (Lisa Carew), Philip Hoffman (John Utterson), Rob Evan (Standby Jekyll/Hyde), and Dave Clemmons (Bishop of Basingstoke).

Co-produced by Jerry Frankel and Jeffrey Richards, and directed by Robin Phillips, the original cast featured Robert Cuccioli as Jekyll and Hyde, Linda Eder as Lucy Harris, and Christiane Noll as Emma Carew, with Rob Evan originally cast as Cuccioli's alternate, performing the title roles at two performances per week (at matinees).

The cast also featured George Robert Merritt as John Utterson, Barrie Ingham as Sir Danvers Carew and Martin Van Treuren as Spider, all of whom played their respective roles throughout the entire run.

The musical played an almost-four-year run and became the longest-running show in the history of the Plymouth Theatre, closing after 1,543 regular performances on January 7, 2001.

[6] The Broadway production was filmed live at the Plymouth Theatre in 2000 with the final cast consisting of David Hasselhoff as Jekyll/Hyde, Coleen Sexton as Lucy and Andrea Rivette as Emma.

[8] The touring company was led by Chuck Wagner in the lead roles, with Sharon Brown as Lucy and Andrea Rivette as Emma.

The tour, which featured Paul Nicholas as Jekyll/Hyde, alongside Louise Dearman as Lucy and Shona Lindsay as Emma, ran through May 21, 2005, and closed in Sunderland.

[10] A second 6-month tour, mainly of the UK and Ireland began on January 20, 2011, in Bromley and ran through July 30 in Leeds, with Marti Pellow as Jekyll/Hyde, Sarah Earnshaw as Emma and Sabrina Carter as Lucy, under the direction of Martin Connors.

The tour, which had various changes to the orchestrations and arrangements of the original score, closed March 31 in Los Angeles in preparation for a pre-planned transfer to Broadway.

The first staged Australian production was by Hayes Theatre Company in July-August 2022, directed by Hayden Tee in a setting revised to the post-World War II era, with chamber orchestration by Nigel Ubrihien and the casting of actress Madeleine Jones in the role of Utterson.

[26] On January 21, 2013, it was announced that Mike Medavoy, Rick Nicita and his production company RPMedia had secured the rights for a feature film version of the musical to be made.

[27] In March 2019, it was announced that Alexander Dinelaris will write the script and produce the movie through his Lexicon banner with Richard Saperstein's Bluestone Entertainment after Medavoy and Nicita's attempt fell through.

The two gentlemen take the audience back some time to find Jekyll in an insane asylum singing of his comatose father ("Lost in the Darkness").

Later that night, a group of high society Londoners turns up at Sir Danvers' residence at Regent's Park, which has a well-maintained façade.

Guinevere, the German manager of "The Red Rat", then breaks Lucy's reverie and then sends her out onstage to do her number ("Bring on the Men"), which captivates Jekyll.

Jekyll approaches Lucy after witnessing the Spider's actions and intends to help her as Utterson is led away by another bar girl.

After insulting the Bishop, Hyde proceeds to beat and stab him to death with the swordstick before gleefully setting the body aflame ("Alive (reprise)").

The citizens of London gossip about the bishop's murder as Hyde hunts down and kills General Glossop, Sir Proops, Lady Beaconsfield, and Lord Savage.

As they leave together, Spider addresses the "Red Rat" attendants, warning them to always be aware of what dangers lie ahead in the East End ("Façade (reprise #3)").

Utterson comes to Jekyll's lab with the rest of the chemicals and a secret envelope and discovers Hyde, who informs him that the doctor is "not available" tonight.

As Utterson leaves, Jekyll mixes in chemicals and injects the new formula, fearing that he might lose himself forever, and praying that he can restore his former life ("No One Must Ever Know").

Utterson visits Lucy at "The Red Rat" with the money, along with a letter from Jekyll that entreats her to leave town and start a new life elsewhere.

As he holds Lucy softly so that she does not suspect it, he slowly, angrily and savagely stabs her multiple times before slitting her throat ("Sympathy, Tenderness (reprise)").

Covered in Lucy's blood, Jekyll returns to his laboratory and faces off with Hyde in a final battle for control ("Confrontation").