During the early period of the COVID-19 pandemic in Serbia, she oversaw the opening of the "Fire Eye" lab, which tested numerous samples.

[10] Ana Brnabić's third ministry was established on 26 October 2022, and Begović was appointed as the minister of science, technological development, and innovation.

[12] In September of the same year, at the initiative of Begović and Serbian prime minister Ana Brnabić, the United Nations General Assembly approved a resolution on the International Decade of Sciences for Sustainable Development.

This was the first time Serbia had initiated and coordinated the adoption of a thematic resolution at the United Nations since rejoining the institution in 2000.

[13] Begović joined with Serbian president Aleksandar Vučić and Brnabić to launch Belgrade's BIO4 campus in December 2023.