Jemeppe-sur-Sambre (French: [ʒəmɛp syʁ sɑ̃bʁ]; Walloon: Djimepe-so-Sambe) is a municipality of Wallonia located in the province of Namur, Belgium.

The total area is 46.80 km2 (18.07 sq mi), giving a population density of 384 inhabitants per km².

The municipality consists of the districts of: Balâtre, Ham-sur-Sambre, Jemeppe-sur-Sambre, Mornimont, Moustier-sur-Sambre, Onoz, Saint-Martin (including the hamlet of Villeret), and Spy.

The Spy Cave, among the most significant Paleolithic sites in Europe, is located in the municipality.

This Namur Province location article is a stub.