The play earned critical acclaim in the 2008 New York International Fringe Festival[12] and had a successful run Off-Broadway.

In 2015, Friedman's solo show American Cunt premiered in the Edinburgh Festival Fringe to critical acclaim.

[16] She created Soft Focus with Jena Friedman, a series of Adult Swim specials that she also co-executive produces, directs, and hosts.

The specials include interviews with John McAfee, the American software entrepreneur and Presidential hopeful,[17][18] as well as Gilberto Valle, a New York City police officer who was convicted of a conspiracy to kidnap, cook, and eat women, known as the "Cannibal Cop".

[27][28] On the day she was scheduled to start her new job, Barr went on a racist Twitter rant that resulted in the show being swiftly cancelled.