The sisters painted Works Progress Administration (WPA), federal government commissioned, murals in midwestern and western states, some as the sole artist and others as Mechau's assistants.
For the Glenwood Springs Post Office, the two artists and another assistant, Edward Chavez, painted Wild Horse Race in 1937.
The three artists also collaborated on Indian Fight and The Corral for the Colorado Springs Post Office, located in Building 41 of the Denver Federal Center.
[9] She collaborated with her sister Ethel on a mural for the Social Security Building (now the Department of Health, Education and Welfare) in c. 1942 in Washington, D.C.[4] Meeting the artists Doris Lee and Arnold Blanch in Los Angeles, the twins learned of the art colony in Woodstock, New York, and traveled there in 1945.
After World War II, Jenne, her husband, Edward Chavez, and her sister, Ethel, relocated to the art colony in Woodstock, New York, where they remained the rest of their lives.
[4][6] Examples of her work are in many venues, including the Grafton Street Junior High School, Worcester, Massachusetts; Woodstock Artist’s Association, New York; and others.