[4] Granick began her career in criminal defense, first at the state public defender's office, then as a trial attorney at the law firm Campbell & DeMetrick.

Granick has been a speaker at conferences such as Def Con and ShmooCon, and has also spoken at the National Security Agency as well as to other law enforcement officials.

[6] She was one of the primary crafters of a 2006 exception to the Digital Millennium Copyright Act which allows mobile telephone owners to legally circumvent the firmware locking their device to a single carrier.

Internet activist Aaron Swartz sought Granick's counsel after his arrest for downloading articles from JSTOR, for which he faced 35 years imprisonment.

[13] The American Civil Liberties Union announced that Granick would be joining the organization as Surveillance and Cybersecurity Counsel in September 2017.