Han made her professional debut on July 31, 2009, losing via majority decision (MD) over four rounds against Melissa St. Vil at the Pan American Center in Las Cruces, New Mexico.
[2] After compiling a record of 10–2–1 (1 KO), she challenged reigning champion Ji-Hye Woo for the IFBA featherweight title on March 23, 2014, at the Wooseul Gymnasium in Haenam, South Korea.
However, Joseph was forced to withdraw from the bout after she was unable to obtain a VISA to enter the U.S.. Fatuma Zarika stepped in as a late replacement, with Han emerging victorious via unanimous decision (UD) to capture the vacant IBF female Intercontinental featherweight title.
On September 4, 2021, at Headingley Rugby Stadium in Leeds, England, she challenged reigning champion Katie Taylor for the undisputed female lightweight championship losing the contest by unanimous decision.
[11] Switching weight divisions again, Han's next fight was a unanimous decision loss to IBF and WBO female super-featherweight world champion Mikaela Mayer at the Orange County Fair & Event Center in Costa Mesa, California, on 9 April 2022.