That same year, Wade appeared in several other films: Wes Craven's drama/thriller Red Eye with Rachel McAdams, Harold Ramis's neo-noir/comedy-drama The Ice Harvest, and the Rob Reiner comedy Rumor Has It with Jennifer Aniston, Kevin Costner, and Shirley MacLaine.

Also in 2005 Wade appeared in John Gulager's horror film Feast, which received a limited theatrical release in the United States in September 2006, playing the role of waitress Honey Pie.

[6][7] In 2006, Wade co-starred with John Patrick Amedori, Lizzy Caplan and Daryl Hannah in Elliott Lester's teen drama, Love Is the Drug, playing the role of "haughty" private school student Erin.

[12] Earlier the same year she was cast on Body Politic, a well-received CW pilot that was not picked up to series,[13] playing the part of Ruby, "an idealistic young staffer".

[14] In 2010, she was cast as Assistant District Attorney Liz Traynor on the short-lived Fox buddy-cop series The Good Guys (originally titled Jack and Dan) alongside Colin Hanks and Bradley Whitford.