[7] Lewis then moved up to the Single-A Kinston Indians in 2006, and had continued success, posting a 7–6 record, a 3.99 ERA, and 94 strikeouts in 108+1⁄3 innings pitched across 21 games (20 starts).

[8] He made his Major League Baseball debut against the Chicago White Sox on July 16, tossing 1+1⁄3 scoreless innings while allowing three walks and striking out two.

[9] Lewis would earn his first big league victory throwing three scoreless innings of relief against the Detroit Tigers on September 18.

[13] Lewis returned on July 4, and served as the Indians' closer in August and September, converting all 13 of his save opportunities.

[11] After a difficult 2011 spring training in which he allowed 10 runs (nine earned) on 13 hits in 5 2/3 innings, Lewis was outrighted to Columbus on March 22.

[7][22] In 2015, Lewis became the pregame/postgame analyst for Cleveland Guardians games on SportsTime Ohio (now Bally Sports Great Lakes).