[3] Jeppesen has offices in locations around the world, including Neu-Isenburg (Germany), Massa (Italy), Crawley (United Kingdom), Gothenburg (Sweden), Canberra (Australia) and Gdańsk (Poland).

Other pilots started to collect data on their own routes and gave it to Jeppesen for him to include in his navigation book.

[8] In 1947, Jeppesen and the Civil Aeronautics Administration (CAA) collaborated to introduce standard instrument approach procedures and to establish the National Flight Data Center.

Between 1990 and 1995, Jeppesen expanded globally by opening offices in Australia and China to serve customers in the Asia-Pacific region, and continued to expand through acquisition by purchasing TannGuide, which became the JeppGuide airport directory; APU, which became part of OpsData; and International Aviation Publishers, which created aviation maintenance training manuals;[9] In 1996, Jeppesen introduced JeppView, which provided a complete, worldwide library of terminal aeronautical charts on CD-ROM; In 1996, Jeppesen acquired MentorPlus, a maker of PC-based aviation and marine moving map and flight planning applications;[9] In 1998 Jeppesen introduced Internet-based delivery of NavData updates.

It has operations in Italy, the United Kingdom, Norway, Greece, Poland, Russia, India, Japan, South Korea, Singapore, Malaysia, Australia and the United States;[13] In 2008, Jeppesen purchased Ocean Systems, Inc., an Alameda, California-based provider of vessel and voyage optimization solutions for commercial marine operations;[9] In 2008, Jeppesen received FAA approval for its Airport Moving Map application for Class 2 electronic flight bags;[9] In 2009, Jeppesen received FAA approval to design and validate required navigation performance (RNP) procedures in the United States;[9] In 2009, Jeppesen sold its Nobeltec product line to Signet USA.

[9] In 2010, Jeppesen received approval from the Civil Aviation Safety Authority of Australia to design, validate and maintain both required navigation performance and conventional instrument approach procedures;[9] In 2010, Jeppesen was named the 2010 INFORMS Prize winner for its organization-wide use of operations research.

[15][16] On October 23, 2006, The New Yorker reported that Jeppesen handled the logistical planning for the CIA's extraordinary rendition flights.

The allegation was based on information from an ex-employee who quoted Bob Overby, the company's managing director, as saying, "We do all of the extraordinary rendition flights—you know, the torture flights.

[17] Jeppesen was named as a defendant in a lawsuit filed by the American Civil Liberties Union (ACLU) on May 30, 2007 on behalf of several others who were allegedly subject to extraordinary rendition.