[2] An extensive notice of his life and thought (Vita) was written by his nephew, a canon of Évora also named Jerónimo Osório, to introduce his edition of his uncle's Complete Works (dedicated to King Philip I of Portugal) published in 1592.

[13] He made such a name that King John III invited him in 1536–1537 to lecture in the reorganized University of Coimbra, where he expounded on Isaiah and on St Paul's Epistle to the Romans.

[22] As the Council of Trent drew towards its close, in 1562, at the prompting of Cardinal Henrique,[23] Osório published a Latin epistle to Queen Elizabeth urging her to return to the Roman Catholic communion and to accept papal authority.

[33] The Cardinal Prince Henry, who had advanced him to the see of Silves, wished to employ him at Lisbon in state business when King Sebastian took up the reins of power in 1568, but Osório excused himself on the ground of his pastoral duties.

[21] In 1571 his extensive History of the reign of King Emmanuel was published at Lisbon,[34] which rendered in his accomplished Latin much of the material in the Chronicle on the same subject by Damião de Góis.

[35] Encompassing the adventures of Vasco da Gama, it coincided with the publication of Os Lusíadas, The Lusiads, of his great contemporary Luís Vaz de Camões.

[37] Sebastian looked with disfavour on opponents of his African adventure, and Osório found it prudent to leave Portugal for Parma and Rome to make a visit ad limina.

[44] It is possible however that the early codex of Tomé Pires' Suma Oriental and the Book of the cartographer Francisco Rodrigues, among the French National Manuscript Collections, belonged to Osório.